Healthzyme

Metformin Medicine  1. Overview Metformin is a first-line oral medication primarily used to manage type 2 diabetes mellitus. It is not used for type 1 diabetes. It works by improving glycemic control with a low risk of hypoglycemia and is often prescribed alongside lifestyle modifications. 2. Mechanism of Action  -Reduces Hepatic Glucose Production:  Inhibits gluconeogenesis in the liver.   Enhances Insulin Sensitivity:  Increases glucose uptake in muscle and adipose tissue.   Delays Intestinal Glucose Absorption: Modestly affects absorption in the gut.   3. Clinical Uses  Type 2 Diabetes: First-line therapy to lower blood glucose.   Off-Label: Polycystic ovary syndrome (PCOS) to improve insulin resistance and regulate menstrual cycles.   4. Dosage Forms & Administration Forms: Immediate-release (IR; 2–3 times daily) and extended-release (XR; once daily).   Dosing:     Start: 500 mg o...